Dorsal root ganglion neurons maintained in a 3D culture model exhibit similar electrophysiological properties to fresh explants.

East, E.; Murphy, K. and Phillips, J. (2011). Dorsal root ganglion neurons maintained in a 3D culture model exhibit similar electrophysiological properties to fresh explants. In: Tissue and Cell Engineering Society, 19-21 July 2011, Leeds.

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Abstract

Tissue engineered culture models provide a powerful tool for neuroscience research1. They overcome limitations associated with monolayer cultures of neurons and glia by maintaining cells in a more realistic 3D spatial arrangement, and permit continuous monitoring and control of variables that cannot be achieved in animal models. Here we report the development of a system for recording electrophysiological behaviour in neurons in 3D culture.

Item Type:	Conference Item
Copyright Holders:	2011 The Authors
ISSN:	1473-2262
Academic Unit/Department:	Science > Life, Health and Chemical Sciences
Item ID:	29160
Depositing User:	James Phillips
Date Deposited:	25 Jul 2011 10:51
Last Modified:	21 Nov 2012 15:38
URI:	http://oro.open.ac.uk/id/eprint/29160

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