Turner, Nicholas W.; Holdsworth, Clovia I.; Donne, Scott W.; McCluskey, Adam and Bowyer, Michael C.
|DOI (Digital Object Identifier) Link:||http://doi.org/10.1039/B9NJ00538B|
|Google Scholar:||Look up in Google Scholar|
Caffeine templated molecularly imprinted polymers (MIPs) have been prepared using identical polymer formulations by thermal and microwave induced initiation, and the binding performance of the systems compared using solid phase extraction (SPE). While the binding capacity of MIP(Microwave) was found to be lower than MIP(Thermal), MIP(Microwave) recorded a higher imprinting factor (IF) due to comparatively low levels of non-specific binding. Selectivity against theophylline in cross-reactivity studies was also found to be greater for MIP(Microwave). While large time savings are achievable through the use of microwave irradiation conditions, physical analysis of the polymers (surface area analysis, thermal gravimetric analysis and differential scanning calorimetry) reveals that the different polymerisation methods lead to differences in both polymer structure and performance.
|Item Type:||Journal Article|
|Copyright Holders:||2010 RSC|
|Academic Unit/Department:||Science > Life, Health and Chemical Sciences
|Interdisciplinary Research Centre:||Centre for Earth, Planetary, Space and Astronomical Research (CEPSAR)
Biomedical Research Network (BRN)
|Depositing User:||Nicholas Turner|
|Date Deposited:||26 Jan 2011 14:42|
|Last Modified:||15 Jan 2016 17:01|
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