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Analytical methods for determination of mycotoxins: A review

Turner, N. W.; Subrahmanyam, S. and Piletsky, S. A. (2009). Analytical methods for determination of mycotoxins: A review. Analytica Chimica Acta, 632(2) pp. 168–180.

DOI (Digital Object Identifier) Link: https://doi.org/10.1016/j.aca.2008.11.010
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Abstract

Mycotoxins are small (MW not, vert, similar700), toxic chemical products formed as secondary metabolites by a few fungal species that readily colonise crops and contaminate them with toxins in the field or after harvest. Ochratoxins and Aflatoxins are mycotoxins of major significance and hence there has been significant research on broad range of analytical and detection techniques that could be useful and practical. Due to the variety of structures of these toxins, it is impossible to use one standard technique for analysis and/or detection. Practical requirements for high-sensitivity analysis and the need for a specialist laboratory setting create challenges for routine analysis. Several existing analytical techniques, which offer flexible and broad-based methods of analysis and in some cases detection, have been discussed in this manuscript. There are a number of methods used, of which many are lab-based, but to our knowledge there seems to be no single technique that stands out above the rest, although analytical liquid chromatography, commonly linked with mass spectroscopy is likely to be popular. This review manuscript discusses (a) sample pre-treatment methods such as liquid–liquid extraction (LLE), supercritical fluid extraction (SFE), solid phase extraction (SPE), (b) separation methods such as (TLC), high performance liquid chromatography (HPLC), gas chromatography (GC), and capillary electrophoresis (CE) and (c) others such as ELISA. Further currents trends, advantages and disadvantages and future prospects of these methods have been discussed.

Item Type: Journal Article
Copyright Holders: 2009 Elsevier
ISSN: 0003-2670
Academic Unit/Department: Faculty of Science, Technology, Engineering and Mathematics (STEM) > Life, Health and Chemical Sciences
Faculty of Science, Technology, Engineering and Mathematics (STEM)
Interdisciplinary Research Centre: Biomedical Research Network (BRN)
Centre for Earth, Planetary, Space and Astronomical Research (CEPSAR)
Item ID: 26983
Depositing User: Nicholas Turner
Date Deposited: 23 Jan 2011 13:08
Last Modified: 17 Nov 2016 14:56
URI: http://oro.open.ac.uk/id/eprint/26983
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