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Radiolabelled Aptamers for Imaging and Therapy

Missailidis, Sotiris and Perkins, Alan (2011). Radiolabelled Aptamers for Imaging and Therapy. In: Speer, Tod ed. Targeted Radionuclide Therapy. Lippincott Williams & Wilkins, pp. 59–68.

URL: http://www.lww.com/product/Targeted-Radionuclide-T...
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Abstract

[About the book]

Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion.

Item Type: Book Chapter
Copyright Holders: 2011 Lippincott Williams & Wilkins
ISBN: 0-7817-9693-8, 978-0-7817-9693-4
Academic Unit/Department: Science > Life, Health and Chemical Sciences
Interdisciplinary Research Centre: Biomedical Research Network (BRN)
Related URLs:
Item ID: 26350
Depositing User: Sotiris Missailidis
Date Deposited: 24 Mar 2011 10:48
Last Modified: 10 Mar 2014 10:31
URI: http://oro.open.ac.uk/id/eprint/26350
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