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Regional expression of synaptic markers in Creutzfeldt-Jakob disease (platform presentation)

Harry-Olatoke, R.; Khan, M.N.; Al-Sarraj, S.; Lantos, P.L.; Anderton, B. and Rezaie, P. (2004). Regional expression of synaptic markers in Creutzfeldt-Jakob disease (platform presentation). In: 105th Meeting of the British Neuropathological Society, 07-09 Jan 2004, Institute of Child Health, London.

URL: http://www.blackwell-synergy.com/doi/pdf/10.1111/j...
DOI (Digital Object Identifier) Link: http://dx.doi.org/10.1111/j.1365-2990.2004.00542.x
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Abstract

Cellular prion protein (PrPe) is a membrane-bound glycoprotein, reportedly expressed at high levels at synapses. The function of PrPe is uncertain. However, the formation of an abnormal isoform (PrPSe) is considered central to the pathogenesis of Creutzfeldt-Jakob disease (CJD), and synaptic damage has been suggested as an early pathological event in CJD.

Item Type: Conference Item
ISSN: 0305-1846
Extra Information: The abstract is published in Neuropathology & Applied Neurobiology, Volume 30 Page 194. See page 195 of PDF at link.
Academic Unit/Department: Science > Life, Health and Chemical Sciences
Interdisciplinary Research Centre: Biomedical Research Network (BRN)
Item ID: 2624
Depositing User: Payam Rezaie
Date Deposited: 14 Jun 2006
Last Modified: 10 Mar 2014 09:26
URI: http://oro.open.ac.uk/id/eprint/2624
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