Development of anti MUC1 DNA aptamers for the imaging and radiotherapy of breast cancer

Da Pieve, C.; Iley, J. N.; Perkins, A. and Missailidis, S. (2006). Development of anti MUC1 DNA aptamers for the imaging and radiotherapy of breast cancer. Breast Cancer Research, 8 pp. 15–16.

URL:	http://www.springerlink.com/content/y517l64447ml85...
DOI (Digital Object Identifier) Link:	http://dx.doi.org/doi:10.1186/bcr1587
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Abstract

Aptamers are novel oligonucleotide-based recognition molecules which can bind to almost any target, including extracellular proteins, antibodies, peptides and small molecules. Aptamers can be rapidly generated, and offer reduced immunogenicity, good tumour penetration, rapid uptake and clearance, and can thus be used as alternatives to monoclonal antibodies in molecular targeted radiotherapy and diagnostic imaging.

Item Type:	Journal Article
Copyright Holders:	2006 BioMed Central Ltd
Extra Information:	Breast Cancer Research Volume 8 Supplement 2, November 2006 Meeting abstracts Breast cancer research: the past and the future The Royal Society, London, UK 1 November 2006 Published online: 1 November 2006
Academic Unit/Department:	Science > Life, Health and Chemical Sciences
Related URLs:	http://breast-cancer-research.com/supple...(Other)
Item ID:	26095
Depositing User:	Sotiris Missailidis
Date Deposited:	05 Apr 2011 09:03
Last Modified:	05 Apr 2011 09:03
URI:	http://oro.open.ac.uk/id/eprint/26095

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