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Developing aptamers as effective anticancer agents or recognition units in biosensor technologies

Simmons, S. C.; Velasco, M. N.; Brenchley, P. E. C.; McKenzie, E. and Missailidis, S. (2008). Developing aptamers as effective anticancer agents or recognition units in biosensor technologies. Anticancer Research, 28(5C) p. 3486.

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Abstract

Aptamers are lengths of single or double stranded nucleotides, typically between 22 and 100 bases long, which can be generated to recognise specific small molecules, peptides, proteins, or even cells and tissues. They have shown great potential as diagnostic and therapeutic agents in anticancer treatment, due to their high specificity and affinity to their target molecules. They have also recently found a niche in the field of biosensing due to their advantages over antibodies; being simpler to synthesise, modify and image, as well as their reported superior affinities and ease of use.

Item Type: Journal Article
Copyright Holders: 2008 Anticancer Research
ISSN: 1791-7530
Extra Information: Abstracts of the 8th International Conference of Anticancer Research, 17-22 October 2008, Kos, Greece
Academic Unit/Department: Science > Life, Health and Chemical Sciences
Interdisciplinary Research Centre: Centre for Earth, Planetary, Space and Astronomical Research (CEPSAR)
Biomedical Research Network (BRN)
Item ID: 26049
Depositing User: Sotiris Missailidis
Date Deposited: 07 Jan 2011 10:44
Last Modified: 09 May 2014 12:48
URI: http://oro.open.ac.uk/id/eprint/26049
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