The Open UniversitySkip to content
 

Aptamers as anticancer agents

Makwana, Vaidehi; Simmons, Suzanne and Missailidis, Sotiris (2008). Aptamers as anticancer agents. In: Missailidis, Sotiris ed. Anticancer Therapeutics. Chichester, UK: Wiley, pp. 331–346.

URL: http://eu.wiley.com/WileyCDA/WileyTitle/productCd-...
Google Scholar: Look up in Google Scholar

Abstract

[About the book]:

This book provides a clear introduction to the area, with an overview of the various drug design and development approaches for cancer therapeutics and their progress in today’s multidisciplinary approach to cancer treatment.

Clearly structured throughout, the book not only provides information on currently used molecular treatment approaches, but also describes the various agents that are currently at various stages of development and clinical trials, thus making them the drugs of tomorrow.

The book goes on to present current therapeutic regimes including their indications and side effects, as well as their position in the international market in terms of sales and development costs. Furthermore, coverage of our advancement in the understanding of cancer biology and how this has driven the drug discovery process is clearly discussed. Modern drug discovery aspects, through genomic, proteomic and metabolomic approaches are referred to as well as combinatorial chemistry techniques and discovery of chemotherapeutic agents from plant extracts, re-use of old drugs and drugs from other indications, or de novo rational drug design.

Including contributions from leading experts in the field, this book provides the reader with a complete overview of the various types of therapeutic agents, current and emerging, as well as other aspects associated with anticancer therapy, drug design, resistance and clinical trials in oncology.

Item Type: Book Chapter
Copyright Holders: 2008 Wiley
ISBN: 0-470-72303-3, 978-0-470-72303-6
Academic Unit/Department: Science > Life, Health and Chemical Sciences
Interdisciplinary Research Centre: Biomedical Research Network (BRN)
Item ID: 26036
Depositing User: Sotiris Missailidis
Date Deposited: 09 Jan 2011 12:26
Last Modified: 10 Mar 2014 10:31
URI: http://oro.open.ac.uk/id/eprint/26036
Share this page:

Actions (login may be required)

View Item
Report issue / request change

Policies | Disclaimer

© The Open University   + 44 (0)870 333 4340   general-enquiries@open.ac.uk