The Open UniversitySkip to content
 

Desorption of small ionic fragments from oligonucleotides induced by low energy carbon ions

Ptasińska, S.; Mason, N. J.; Hunniford, C. A.; McCullough, R. W.; Denifl, A.; Mauracher, A. and Scheier, P. (2010). Desorption of small ionic fragments from oligonucleotides induced by low energy carbon ions. European Physical Journal D - Atomic, Molecular and Optical Physics, 60(1) pp. 59–63.

Full text available as:
Full text not publicly available (Version of Record)
Due to publisher licensing restrictions, this file is not available for public download
DOI (Digital Object Identifier) Link: https://doi.org/10.1140/epjd/e2010-00083-x
Google Scholar: Look up in Google Scholar

Abstract

The degradation of oligonucleotide films containing differing base sequences induced by 4 keV C+ ions has been studied experimentally. The oligonucleotides were deposited onto a gold coated stainless steel substrate and the anions and cations released from the films were analyzed by a quadrupole mass spectrometer. The total ion desorption yield was recorded as a function of time using a constant C+ ion flux of 6 × 1014 ions cm-2 s-1. At low fluences the formation of small ionic fragments was observed, whilst for fluences greater than 1.2 × 1018 ions cm-2 molecules were sputtered from the substrate. In addition to studies of the influence of a particular base to the total cation desorption yield, the effect of base substitution with bromine was measured for negative ion desorption. These results showed a strong degradation of oligonucleotide films during ion bombardment.

Item Type: Journal Item
Copyright Holders: 2010 EDP Sciences, Società Italiana di Fisica, Springer-Verlag
ISSN: 1434-6060
Extra Information: From the issue entitled "Molecular level assessments of radiation biodamage"
Academic Unit/School: Faculty of Science, Technology, Engineering and Mathematics (STEM) > Physical Sciences
Faculty of Science, Technology, Engineering and Mathematics (STEM)
Research Group: Physics
Item ID: 25491
Depositing User: Astrid Peterkin
Date Deposited: 15 Dec 2010 14:11
Last Modified: 11 Dec 2018 16:16
URI: http://oro.open.ac.uk/id/eprint/25491
Share this page:

Metrics

Altmetrics from Altmetric

Citations from Dimensions

Actions (login may be required)

Policies | Disclaimer

© The Open University   contact the OU