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The epidemiology of transmissible diseases after elimination

De Serres, Gaston; Gay, Nigel J. and Farrington, C. Paddy (2000). The epidemiology of transmissible diseases after elimination. American Journal of Epidemiology, 151(11) pp. 1039–1048.

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Elimination of an infectious disease is often understood to mean the total absence of cases in a population. This situation can occur only if the entire population is immune as a result of either natural disease or vaccination. However, this costly and unrealistic scenario is not necessary to ensure elimination, more appropriately defined as a situation in which sustained transmission cannot occur and secondary spread from importations of disease will end naturally, without intervention. The authors describe the size and duration of outbreaks caused by imported infections after indigenous transmission has been eliminated. They show that the status of the elimination process can be monitored by assessing the proportion of cases imported and the distribution of outbreak sizes. Measles in Canada, the United States, and the United Kingdom provides a good example of the relevance of these criteria. Surveillance of the size and duration of these outbreaks enables maintenance of elimination to be monitored.

Item Type: Journal Item
Copyright Holders: 2000 The Johns Hopkins University School of Hygiene and Public Health
ISSN: 1476-6256
Project Funding Details:
Funded Project NameProject IDFunding Body
Not SetNot SetQuebec Ministry of Health and Social Services, Canada
Keywords: communicable disease control/methods; communicable diseases/transmission; disease outbreaks/prevention & control; epidemiologic methods; immunity; vaccination
Academic Unit/School: Faculty of Science, Technology, Engineering and Mathematics (STEM) > Mathematics and Statistics
Faculty of Science, Technology, Engineering and Mathematics (STEM)
Item ID: 23411
Depositing User: Sarah Frain
Date Deposited: 04 Apr 2011 14:38
Last Modified: 07 Dec 2018 09:40
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