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Farrington, Paddy
(2004).
DOI: https://doi.org/10.1093/aje/kwh093
Abstract
Ki et al. used a case-crossover design to evaluate the relative risk of aseptic meningitis after measles-mumps-rubella vaccination. Although their results are broadly in line with those of others on the same topic, the case-crossover design cannot generally be recommended for investigating associations between adverse events and childhood immunizations because it requires the probability of exposure (i.e., vaccination) to be constant over time. This requirement is certainly not met by childhood immunizations administered according to highly age-dependent schedules. Measles-mumps-rubella vaccines, for example, are typically given at 12–15 months of age.
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- Item ORO ID
- 22610
- Item Type
- Journal Item
- ISSN
- 1476-6256
- Academic Unit or School
-
Faculty of Science, Technology, Engineering and Mathematics (STEM) > Mathematics and Statistics
Faculty of Science, Technology, Engineering and Mathematics (STEM) - Copyright Holders
- © 2004 The Author
- Depositing User
- Sarah Frain