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Parvovirus B19 viraemia in Dutch blood donors

Zaaijer, H. L.; Koppelman, M. H. G. M. and Farrington, C. P. (2004). Parvovirus B19 viraemia in Dutch blood donors. Epidemiology and Infection, 132(6) pp. 1161–1166.

DOI (Digital Object Identifier) Link: http://dx.doi.org/10.1017/S0950268804002730
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Abstract

Blood, donated by asymptomatic donors, may contain and transmit parvovirus B19. To investigate the dynamics of parvovirus viraemia in asymptomatic blood donors, we studied the amounts of parvovirus DNA in pools of donor plasma, the prevalence of parvovirus antibodies among blood donors in relation to age, and the seasonal and year-to-year variation of the incidence of parvovirus infection in The Netherlands. The incidence of parvovirus infection follows a seasonal cycle and a cycle of several years. Among Dutch blood donors the incidence was estimated to be 0·56% per year. Forty seven out of 100 pools of 5000 plasma donations tested positive for parvovirus DNA. We inferred that the course of viraemia in asymptomatic donors shows a short peak (>109 copies parvovirus DNA/ml), followed by viraemia below 106 copies/ml for about 2 weeks.

Item Type: Journal Article
Copyright Holders: 2004 Cambridge University Press
ISSN: 0950-2688
Academic Unit/Department: Mathematics, Computing and Technology > Mathematics and Statistics
Item ID: 22598
Depositing User: Sarah Frain
Date Deposited: 17 Aug 2010 11:28
Last Modified: 02 Dec 2010 21:01
URI: http://oro.open.ac.uk/id/eprint/22598
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