New methodologies for the synthesis of 3-acylpyridone metabolites

Jones, Raymond C. F.; Choudhury, Abdul K.; Iley, James N.; Loizou, Georgia; Lumley, Christopher and McKee, Vickie (2010). New methodologies for the synthesis of 3-acylpyridone metabolites. Synlett(4) pp. 654–658.

DOI: https://doi.org/10.1055/s-0029-1219341

Abstract

A core isoxazolo[4,3-c]pyridin-4-one scaffold is prepared and elaborated at C-3(Me) and C-7 as a masked building block for 3-acylpyridin-2-ones related to the acylpyridone natural products.

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About

  • Item ORO ID
  • 20972
  • Item Type
  • Journal Item
  • ISSN
  • 0936-5214
  • Keywords
  • heterocycles; cycloaddition; metalation; aldol reaction; pyridone
  • Academic Unit or School
  • Other Departments > Other Departments
    Other Departments
  • Copyright Holders
  • © 2010 Georg Thieme Verlag Stuttgart
  • Depositing User
  • James Iley

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