Vu, Kiem; Weksler, Babette; Romero, Ignacio A; Couraud, Pierre-Olivier and Gelli, Angie
(2009).
Immortalized Human Brain Endothelial Cell Line HCMEC/D3 as a Model of the Blood-Brain Barrier Facilitates In Vitro Studies of Central Nervous System Infection by Cryptococcus neoformans.
Eukaryotic Cell, 8(11)
pp. 1803–1807.
(
Click here to request a copy from the OU Author.)
Abstract
Cryptococcus neoformans cells must cross the blood-brain barrier prior to invading the central nervous system. Here we demonstrate that the immortalized human brain endothelial cell line HCMEC/D3 is a useful alternative to primary brain endothelial cells as a model of the blood-brain barrier for studies of central nervous system infection.
| Item Type: |
Journal Article
|
| Copyright Holders: |
2009 American Society for Microbiology |
| ISSN: |
1535-9786 |
| Keywords: |
Cryptococcus neoformans cells; CNS; central nervous system; endothelial cells; blood-brain barrier |
| Academic Unit/Department: |
Science > Life, Health and Chemical Sciences |
| Item ID: |
19390 |
| Depositing User: |
Users 9108 not found. |
| Date Deposited: |
06 Jan 2010 15:17 |
| Last Modified: |
14 Nov 2012 11:56 |
| URI: |
http://oro.open.ac.uk/id/eprint/19390 |
Actions (login may be required)
