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Optical assay for biotechnology and clinical diagnosis

Moczko, Ewa; Cauchi, Michael; Turner, Claire; Meglinski, Igor and Piletsky, Sergey (2011). Optical assay for biotechnology and clinical diagnosis. IEEE Transactions on Biomedical Engineering, 58(8) pp. 2154–2160.

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DOI (Digital Object Identifier) Link: http://doi.org/10.1109/TBME.2011.2113348
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Abstract

In this paper, we present an optical diagnostic assay consisting of a mixture of environmental-sensitive fluorescent dyes combined with multivariate data analysis for quantitative and qualitative examination of biological and clinical samples. The performance of the assay is based on the analysis of spectrum of the selected fluorescent dyes with the operational principle similar to electronic nose and electronic tongue systems. This approach has been successfully applied for monitoring of growing cell cultures and identification of gastrointestinal diseases in humans.

Item Type: Journal Article
Copyright Holders: 2011 IEEE
ISSN: 0018-9294
Keywords: chemometrics; clinical applications; fluorescence dyes; optical diagnosis
Academic Unit/Department: Science > Life, Health and Chemical Sciences
Science
Interdisciplinary Research Centre: Centre for Earth, Planetary, Space and Astronomical Research (CEPSAR)
Biomedical Research Network (BRN)
Item ID: 19152
Depositing User: Claire Turner
Date Deposited: 14 Jul 2011 09:32
Last Modified: 25 Feb 2016 11:07
URI: http://oro.open.ac.uk/id/eprint/19152
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