Optical assay for biotechnology and clinical diagnosis

Moczko, Ewa; Cauchi, Michael; Turner, Claire; Meglinski, Igor and Piletsky, Sergey (2011). Optical assay for biotechnology and clinical diagnosis. IEEE Transactions on Biomedical Engineering, 58(8) pp. 2154–2160.

DOI: https://doi.org/10.1109/TBME.2011.2113348

Abstract

In this paper, we present an optical diagnostic assay consisting of a mixture of environmental-sensitive fluorescent dyes combined with multivariate data analysis for quantitative and qualitative examination of biological and clinical samples. The performance of the assay is based on the analysis of spectrum of the selected fluorescent dyes with the operational principle similar to electronic nose and electronic tongue systems. This approach has been successfully applied for monitoring of growing cell cultures and identification of gastrointestinal diseases in humans.

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About

• Item ORO ID
• 19152
• Item Type
• Journal Item
• ISSN
• 0018-9294
• Keywords
• chemometrics; clinical applications; fluorescence dyes; optical diagnosis
• Academic Unit or School
• Faculty of Science, Technology, Engineering and Mathematics (STEM) > Life, Health and Chemical Sciences
  Faculty of Science, Technology, Engineering and Mathematics (STEM)
• Research Group
• Innovation, Knowledge & Development research centre (IKD)
• Copyright Holders
• © 2011 IEEE
• Depositing User
• Claire Turner