Wright, K. E. and Phillips, J. B.
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Photodynamic therapy (PDT) is a promising treatment modality for cancer which involves administration of a photosensitising agent that can be activated subsequently within a patient's cells, resulting in cell death from oxidative damage. Peripheral nerve sparing has been reported following PDT with the photosensitiser meta(tetra-hydroxyphenyl) chlorin (mTHPC) [1 & 2]. Dorsal root ganglia (DRG) neurons have been shown to be relatively insensitive to mTHPC-PDT doses that killed other cell types in a 3D collagen culture system . The aim here was to determine the extent to which 'surviving' neurons were able to sprout neurites as an indication of functional recovery following PDT.
|Item Type:||Conference Item|
|Copyright Holders:||2009 Unknown|
|Project Funding Details:||
|Extra Information:||Poster presentation at Annual meeting of the Tissue and Cell Engineering Society (TCES2009); July 8-10 2009, University of Glasgow, Glasgow, UK; Centre for Cell Engineering (University of Glasgow) and Laboratory for Biomolecular Nanotechnology (University of Strathclyde).
|Academic Unit/Department:||Science > Life, Health and Chemical Sciences
|Interdisciplinary Research Centre:||Biomedical Research Network (BRN)|
|Depositing User:||James Phillips|
|Date Deposited:||15 Dec 2009 13:54|
|Last Modified:||25 Feb 2016 13:46|
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