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Characterising regional ultrastructure in peripheral nerves

Mason, S.; Harle, J. and Phillips, J. B. (2009). Characterising regional ultrastructure in peripheral nerves. In: European Cells and Materials, 18(Sup 2) p. 77.

URL: http://www.ecmjournal.org/journal/supplements/vol0...
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Abstract

Peripheral nerve repair is often compromised by a failure to restore the biomechanical integrity of damaged nerves. Restoration of the tensile properties of nerves, in particular their ability to bend and stretch during limb movement, is an important consideration in the design of tissue engineered repair conduits and other repair approaches. An understanding of the mechanical architecture of peripheral nerves that underpins their tensile properties is therefore desirable. Previous research has identified that the stiffness of rat peripheral nerves varies longitudinally according to where they traverse joints. This study explores how ultrastructural features such as the size-distribution of collagen fibrils and the thickness of the perineurium vary in specific regions of rat sciatic nerves.

Item Type: Conference Item
Copyright Holders: 2009 The Authors
ISSN: 1473-2262
Extra Information: Poster presentation at Tissue and Cell Engineering Society (TCES) meeting 8-10 July 2009, Universities of Glasgow & Strathclyde
Academic Unit/Department: Science > Life, Health and Chemical Sciences
Science
Science > Physical Sciences
Interdisciplinary Research Centre: Biomedical Research Network (BRN)
Related URLs:
Item ID: 17848
Depositing User: James Phillips
Date Deposited: 15 Dec 2009 13:47
Last Modified: 15 Jan 2016 11:42
URI: http://oro.open.ac.uk/id/eprint/17848
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