Musonda, Patrick; Hocine, Mounia N.; Andrews, Nick J.; Tubert-Bitter, Pascale and Farrington, Paddy C.
Monitoring vaccine safety using case series cumulative sum charts.
Vaccine, 26(42) pp. 5358–5367.
We adapt the self-controlled case series method for routine surveillance of vaccine safety using cumulative sum (CUSUM) charts. The CUSUM surveillance method we propose is applicable for detecting associations that arise in a short pre-determined risk period following vaccination. The performance of the case series CUSUM is investigated through simulations. We illustrate the method using retrospective analyses of influenza vaccine and Bell's palsy, and MMR vaccine and febrile convulsions.
||2008 Elsevier Ltd.
|Project Funding Details:
|Funded Project Name||Project ID||Funding Body|
|Not Set||Not Set||MRC|
|Not Set||Not Set||EPSRC|
|Not Set||Not Set||Fondation pour la Recherche Médicale|
||adverse event; self-controlled case series method; CUSUM; average run length; surveillance; vaccine
||Mathematics, Computing and Technology > Mathematics and Statistics
||14 Apr 2009 20:02
||20 Mar 2014 14:51
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