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The analytical characteristics of aptamers are comparable with those of antibodies for the development of biosensor technology. However, aptamers offer some crucial advantages over antibodies such as selection capability for a variety of targets, easy synthesis, improved reproducibility and stability, simple modification for immobilization to solid supports and enhanced selectivity. This article reviews aptamer technology as well as aptamer-based assay configurations and goes on to explore reported applications in electrochemical aptasensors.
|Item Type:||Journal Article|
|Copyright Holders:||2009 Gene Therapy Press|
|Keywords:||aptamer; biosensor; electrochemical detection; SELEX|
|Academic Unit/Department:||Science > Life, Health and Chemical Sciences
|Interdisciplinary Research Centre:||Centre for Earth, Planetary, Space and Astronomical Research (CEPSAR)
Biomedical Research Network (BRN)
|Depositing User:||Maria Velasco|
|Date Deposited:||17 Mar 2009 17:31|
|Last Modified:||23 Feb 2016 21:07|
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