Velasco-Garcia, Maria and Missailidis, Sotiris
New trends in aptamer-based electrochemical biosensors.
Gene Therapy and Molecular Biology, 13(1),
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The analytical characteristics of aptamers are comparable with those of antibodies for the development of biosensor technology. However, aptamers offer some crucial advantages over antibodies such as selection capability for a variety of targets, easy synthesis, improved reproducibility and stability, simple modification for immobilization to solid supports and enhanced selectivity. This article reviews aptamer technology as well as aptamer-based assay configurations and goes on to explore reported applications in electrochemical aptasensors.
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