Wright, K. E.; MacRobert, A. J. and Phillips, J. B.
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The effect of photodynamic therapy (PDT) on the cells of the nervous system is an important consideration in the treatment of tumours that are located within or adjacent to the brain, spinal cord and peripheral nerves. Previous studies have reported the sparing of nerves during PDT using meta-tetrahydroxyphenylchlorin (mTHPC, Foscan®) in patients and in animal models. The aim of this study was to investigate the effects of mTHPC on key nervous system cells using a 3-dimensional cell culture system for the accurate detection of differences in sensitivity.
|Item Type:||Conference Item|
|Keywords:||mTHPC; neurons; satellite glia; MCF-7; astrocytes; photodynamic therapy;|
|Academic Unit/Department:||Science > Life, Health and Chemical Sciences
|Interdisciplinary Research Centre:||Biomedical Research Network (BRN)|
|Depositing User:||James Phillips|
|Date Deposited:||22 Oct 2008 10:28|
|Last Modified:||15 Jan 2016 15:13|
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