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Ptasińska, Sylwia; Stypczynska, Agnieszka; Nixon, Tony; Mason, Nigel; Klyachko, DV and Sanche, L
(2008).
DOI: https://doi.org/10.1063/1.2961027
Abstract
In this work, the chemical changes in calf thymus DNA samples were analyzed by X-ray photoelectron spectroscopy XPS. The DNA samples were irradiated for over 5 h and spectra were taken repeatedly every 30 min. In this approach the X-ray beam both damages and probes the samples. In most cases, XPS spectra have complex shapes due to contributions of C, N, and O atoms bonded at several different sites. We show that from a comparative analysis of the modification in XPS line shapes of the C 1s, O 1s, N 1s, and P 2p peaks, one can gain insight into a number of
reaction pathways leading to radiation damage to DNA.
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- Item ORO ID
- 11389
- Item Type
- Journal Item
- Academic Unit or School
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Faculty of Science, Technology, Engineering and Mathematics (STEM) > Physical Sciences
Faculty of Science, Technology, Engineering and Mathematics (STEM)
Faculty of Science, Technology, Engineering and Mathematics (STEM) > Engineering and Innovation - Research Group
- Physics
- Copyright Holders
- © 2008 American Institute of Physics
- Depositing User
- Astrid Peterkin