Ptasinska, Sylwia; Stypczynska, Agnieszka; Nixon, Tony; Mason, Nigel; Klyachko, DV and Sanche, L
(2008).
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| DOI (Digital Object Identifier) Link: | http://dx.doi.org/doi:10.1063/1.2961027 |
|---|---|
| Google Scholar: | Look up in Google Scholar |
Abstract
In this work, the chemical changes in calf thymus DNA samples were analyzed by X-ray photoelectron spectroscopy XPS. The DNA samples were irradiated for over 5 h and spectra were taken repeatedly every 30 min. In this approach the X-ray beam both damages and probes the samples. In most cases, XPS spectra have complex shapes due to contributions of C, N, and O atoms bonded at several different sites. We show that from a comparative analysis of the modification in XPS line shapes of the C 1s, O 1s, N 1s, and P 2p peaks, one can gain insight into a number of
reaction pathways leading to radiation damage to DNA.
| Item Type: | Journal Article |
|---|---|
| Copyright Holders: | 2008 American Institute of Physics |
| Academic Unit/Department: | ?? scie-phya ?? Science > Physical Sciences Mathematics, Computing and Technology > Communication and Systems |
| Interdisciplinary Research Centre: | Centre for Earth, Planetary, Space and Astronomical Research (CEPSAR) |
| Item ID: | 11389 |
| Depositing User: | Astrid Peterkin |
| Date Deposited: | 18 Aug 2008 12:46 |
| Last Modified: | 25 Oct 2012 22:51 |
| URI: | http://oro.open.ac.uk/id/eprint/11389 |
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