Probing Radiation Damage at the Molecular Level

Mason, N. J.; Smialek, M. A.; Moore, S. A.; Folkard, M. and Hoffmann, S. V. (2006). Probing Radiation Damage at the Molecular Level. In: Proceedings of 23rd SPIG meeting AIP Conference Proceedings, 28 Aug - 1 Sep 2006, Serbia.

DOI: https://doi.org/10.1063/1.2406009

URL: http://scitation.aip.org/getabs/servlet/GetabsServ...

Abstract

Radiation damage of DNA and other cellular components has traditionally been attributed to ionisation via direct impact of high-energy quanta or by complex radical chemistry. However recent research has shown that strand breaks in DNA may be initiated by secondary electrons and is strongly dependent upon the target DNA base identity. Such research provides the fascinating perspective that it is possible that radiation damage may be described and understood at an individual molecular level introducing new possibilites for therapy and perhaps providing an insight into the origins of life.

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About

• Item ORO ID
• 10776
• Item Type
• Conference or Workshop Item
• Extra Information
• Published in AIP Conference Proceedings, Volume 876, pp. 3-14
• Academic Unit or School
• Faculty of Science, Technology, Engineering and Mathematics (STEM) > Physical Sciences
  Faculty of Science, Technology, Engineering and Mathematics (STEM)
• Research Group
• Physics
• Depositing User
• Astrid Peterkin